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Updated: May 19, 2026

10:43
Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas
Published on: July 21, 2023
Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular
Fenglei Gao1, Zhu Zhu, Jianping Lei
1State Key Laboratory of Analytical Chemistry for Life Science, Department of Chemistry, Nanjing University, Nanjing 210093, PR China.
Abstract:
A novel strategy of dual signal amplification was developed using circular strand-replacement DNA polymerization with a molecular beacon as a switch and silver enhancement on magnetic nanoparticles for the specific Raman spectroscopic detection of DNA down to the sub-picomolar level.

