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Related Experiment Video

Updated: May 19, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Anterior skull base surgery.

Moni Abraham Kuriakose1, Nirav P Trivedi, Vikram Kekatpure

  • 1Department of Head and Neck Oncology, Mazumdar Shaw Cancer Center Narayana Health City, Bangalore, 560 099 India.

Indian Journal of Surgical Oncology
|August 30, 2012
PubMed
Summary

Achieving negative surgical margins is key for successful anterior skull base tumor resection. Advances in surgical techniques improve outcomes for these challenging tumors.

Related Concept Videos

Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...

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Area of Science:

  • Neurosurgery
  • Oncology
  • Surgical Oncology

Background:

  • Anterior skull base tumors present complex surgical challenges.
  • Achieving negative margins is crucial for prognosis in skull base tumor surgery.
  • Traditional open approaches are standard for malignant tumors, while benign lesions may allow for minimally invasive options.

Purpose of the Study:

  • To review surgical approaches for anterior skull base tumors.
  • To discuss relevant anatomy and pathology.
  • To highlight advancements in surgical techniques and their impact on outcomes.

Main Methods:

  • Review of literature on anterior skull base surgery.
  • Description of various surgical approaches, including open and minimally invasive techniques.
Keywords:
Anterior skull base surgeryCraniofacial resectionSkull base reconstructionSkull base surgery

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Last Updated: May 19, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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  • Discussion of anatomical considerations and tumor pathology.

    • Main Results:

    • Negative surgical margins are the primary prognostic factor.
    • Facial translocation approaches offer wide tumor exposure with minimal brain retraction.
    • Outcomes for anterior skull base tumors have improved, with disease-free survival rates now comparable to other head and neck malignancies.

    Conclusions:

    • Surgical approach selection is critical for optimal tumor resection.
    • Technological advancements enhance surgical capabilities and patient outcomes.
    • Continued research into surgical techniques and management strategies is essential for improving the prognosis of anterior skull base tumors.