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Updated: May 19, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
Chances and risks of predicting psychosis.
Stephan Ruhrmann1, Joachim Klosterkötter, Mitja Bodatsch
1Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany. stephan.ruhrmann@uk-koeln.de
Preventing psychosis shows promise, but prediction errors can cause harm. Careful risk assessment is crucial to balance intervention benefits against potential harms for individuals at risk.
Area of Science:
- Psychiatry and Mental Health
- Clinical Psychology
- Neuroscience
Background:
- Psychosis prevention is a key strategy, but predictive models have inherent error probabilities.
- False risk attribution can lead to unnecessary stress, anxiety, and interventions.
- Clinical risk samples often present with existing psychopathology and impairments.
Purpose of the Study:
- To explore the benefits and costs of psychosis prevention strategies.
- To address challenges in differentiating normal from clinically relevant mental states.
- To investigate the impact of stigmatization in psychosis risk assessment.
Main Methods:
- Review of current strategies for psychosis prevention.
- Analysis of the implications of prediction error in risk assessment.
- Discussion on the need for advanced risk algorithms and multi-step detection.
Main Results:
- Weighing benefits and costs of preventive interventions is essential due to prediction errors.
- Psychotic-like phenomena are common in adolescents, complicating risk assessment.
- Severe risk states may lead to self-stigmatization, independent of diagnosis.
Conclusions:
- Preventive measures should integrate treatment for current complaints to minimize futile interventions.
- Improved validity of risk criteria requires advanced algorithms and risk stratification.
- The decision to implement preventive measures must balance intervention costs against avoiding severe outcomes.
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