Related Experiment Video

Updated: May 19, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding

Andrew Holmes1, Paul J Fitzgerald, Kathryn P MacPherson

  • 1Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, Bethesda, Maryland, USA. andrew.holmes@nih.gov

Nature Neuroscience
|September 4, 2012
PubMed

More Related Videos

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD06:09

Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD

Published on: February 2, 2017

Related Concept Videos

CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...