Related Experiment Video
Updated: May 18, 2026

Management of the Uncinate Process in No-Touch Laparoscopic Pancreaticoduodenectomy
Published on: May 5, 2023
The normal uncinate process: histology and clinical relevance
Gilead Berger1, Ephraim Eviatar, Tatiana Kogan
1Ear, Nose, and Throat Histopathological Research Laboratory of Department of Otolaryngology-Head and Neck Surgery, Meir Medical Center, 59 Tchernichovsky St., Kfar Saba, 44281, Israel. berger45@netvision.net.il
This study details the histology and morphometry of the uncinate process (UP), revealing distinct tissue characteristics compared to turbinates. Findings support preserving UP anatomy in chronic sinus disease management.
Area of Science:
- Otorhinolaryngology
- Anatomy
- Histology
Background:
- The uncinate process (UP) is a key anatomical structure in the ethmoid infundibulum.
- Understanding its histological and morphometric properties is crucial for sinus surgery.
Purpose of the Study:
- To conduct a detailed histological and morphometric assessment of the normal uncinate process (UP).
- To compare the UP's soft tissue and bony elements with neighboring inferior and middle turbinates.
- To inform surgical approaches for chronic rhinosinusitis.
Main Methods:
- Prospective, non-randomized, controlled trial across three centers.
- Histological and morphometric analysis of 16 adult UP samples.
- Comparison with 28 age- and gender-matched archival turbinate samples.
Main Results:
- UP mucosal layers contain loose connective tissue, inflammatory cells, glands, and venules.
- UP bone is either thin lamellar compact bone or thicker cancellous bone.
- Significant differences observed in connective tissue, gland, and vein area fractions compared to turbinates.
Conclusions:
- The uncinate process (UP) exhibits unique histological and morphometric features.
- These differences suggest distinct physiological roles for the UP compared to turbinates.
- Preserving UP anatomy with bone- and mucosa-sparing techniques is recommended for chronic sinus disease.
Related Concept Videos
Histology of the Small Intestine
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Histology of the Uterus
The endometrium is the...
Histology of the Large Intestine
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Histology of the Gastrointestinal (GI) Tract
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

