Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atelectasis II: Pathophysiology

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...

Pulmonary Cycle: Exhalation

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

Pneumothorax II: Pathophysiology

Pneumothorax II: Pathophysiology

Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

Chronic Obstructive Pulmonary Disease II: Emphysema

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.

Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dose-Dependent Cytotoxic Effects of Lavandula angustifolia L. Oil on A549 Human Lung Carcinoma Cells.

Medical science monitor : international medical journal of experimental and clinical research·2026

Same author

Multicenter Investigation of Current Asthma Coexistence in Allergic Rhinitis Cases.

The Journal of craniofacial surgery·2025

Same author

Cough: A Reflex That Disrupts Interpersonal Communication.

The Journal of craniofacial surgery·2025

Same author

How Propolis Prevents Nicotine-Related Lung Damage.

The Journal of craniofacial surgery·2025

Same author

Protective Effects of Melatonin Against PM2.5-Induced Lung Damage.

The Journal of craniofacial surgery·2025

Same author

Multicenter Investigation of Current Allergic Rhinitis Coexistence in Asthma Patients.

The Journal of craniofacial surgery·2025

Search research articles

Related Experiment Video

Updated: May 18, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Round atelectasis in sarcoidosis.

Cuneyt Tetikkurt¹, Seza Tetikkurt, Imran Ozdemir

¹Pulmonary Diseases Department, Cerrahpasa Medical Faculty, Istanbul University, Turkey. docmct@superonline.com.

Multidisciplinary Respiratory Medicine

|September 11, 2012

Summary

Round atelectasis, a pleural condition, was observed in four sarcoidosis patients. This finding suggests sarcoidosis may be an underlying cause of round atelectasis, previously unlinked to this disease.

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Related Experiment Videos

Last Updated: May 18, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Area of Science:

Pulmonology
Pathology

Background:

Round atelectasis is a benign pleural inflammatory condition often linked to asbestos exposure or chronic infections.
Previously, round atelectasis has not been documented in patients with sarcoidosis.

Purpose of the Study:

To report the occurrence of round atelectasis in patients diagnosed with sarcoidosis.
To investigate the potential link between sarcoidosis and the development of round atelectasis.

Main Methods:

Case series of four patients with pre-existing sarcoidosis.
Clinical evaluation including symptom assessment (thoracic pain, cough).
Diagnostic imaging (chest roentgenogram, CT scan) and histopathological confirmation via fiberoptic bronchoscopy and transbronchial lung biopsy.

Main Results:

Four sarcoidosis patients presented with round atelectasis.
Radiological findings showed subpleural opacities consistent with round atelectasis.
Histopathology confirmed the diagnosis in all cases.

Conclusions:

Sarcoidosis should be considered as a potential etiological factor for round atelectasis.
Mechanical effects from prior sarcoidosis-related pleural effusions may contribute to round atelectasis development.