Related Experiment Video
Updated: May 18, 2026
12:23
Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Visual outcome following optic neuritis: a 5-year review
C N Pedro-Egbe1, B Fiebai, C S Ejimadu
1Ophthalmology Unit, Department of Surgery, College of Health Sciences, University of Port Harcourt, Nigeria.
Nigerian Journal of Clinical Practice
|September 11, 2012
Summary
Optic neuritis patients in Nigeria showed significant visual acuity improvement within 12 weeks post-attack. Despite good recovery, long-term follow-up is recommended due to potential demyelination complications.
Area of Science:
- Ophthalmology
- Neurology
Background:
- Optic neuritis is a common demyelinating inflammatory optic nerve disease, particularly affecting young women.
- It is often associated with multiple sclerosis, especially in Caucasian populations.
- While visual recovery is typical, the quality of vision can be compromised.
Purpose of the Study:
- To assess the degree of visual improvement following an optic neuritis episode in Port Harcourt, Nigeria.
Main Methods:
- A retrospective hospital-based study was conducted at the University of Port Harcourt Teaching Hospital.
- Data from 27 optic neuritis cases between 2006 and 2010 were analyzed.
- Visual acuity at presentation and 12 weeks post-treatment was recorded.
Main Results:
- Optic neuritis accounted for 0.1% of patients seen (27 cases).
- The majority of cases (74.1%) were retro-bulbar neuritis.
- Most patients (75%) presented with visual acuity worse than 6/24, with 77.1% improving to 6/12 or better by 12 weeks.
Conclusions:
- Visual acuity significantly improves after optic neuritis attacks, consistent with global findings.
- Although the risk of multiple sclerosis is lower in Black populations, continued monitoring for demyelination complications is advised.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...