Related Experiment Video
Updated: May 18, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilia in the returning traveler
Andrew Ustianowski1, Alimuddin Zumla
1Regional Infectious Diseases Unit, North Manchester General Hospital, Manchester, UK. andrew.ustianowski@pat.nhs.uk
Infectious Disease Clinics of North America
|September 12, 2012
Summary
Elevated eosinophil counts in travelers often indicate helminth infections. Early diagnosis and understanding the causes of eosinophilia are crucial for preventing severe health outcomes.
Area of Science:
- Tropical medicine
- Parasitology
- Clinical diagnostics
Background:
- Elevated eosinophil counts are common in returning travelers.
- Eosinophilia is often underrecognized in this population.
- Helminth infections are a frequent cause of eosinophilia in travelers.
Purpose of the Study:
- To outline the causes and diagnosis of eosinophilia in travelers.
- To focus on helminth infections as a primary etiology.
- To highlight the clinical significance of eosinophilia.
Main Methods:
- Review of literature on eosinophilia in travelers.
- Analysis of etiological factors, particularly helminth infections.
- Discussion of diagnostic approaches for eosinophilia.
Main Results:
- Helminth infections are a significant cause of eosinophilia in travelers.
- Eosinophilia can range from benign to severe conditions.
- Accurate diagnosis is key to appropriate management.
Conclusions:
- Recognizing and diagnosing eosinophilia in travelers is essential.
- Helminth infections require prompt identification and treatment.
- Understanding eosinophilia aids in preventing severe sequelae.
More Related Videos
Related Concept Videos
01:28Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
02:06Allergic Reactions
Overview
01:13Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
01:30Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
01:27Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...