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Updated: May 18, 2026

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
5-Amino-3-anilino-1H-pyrazole-4-carbonitrile
Abstract:
In the title compound, C(10)H(9)N(5), the phenyl ring is twisted with respect to the pyrazole ring, forming a dihedral angle of 24.00 (6)°. In the crystal, mol-ecules are linked by N-H⋯N hydrogen bonds into chains running parallel to [010] containing alternating R(2) (2)(6) and R(2) (2)(12) rings. Further inter-actions are found in the crystal, viz. N-H⋯π(phen-yl) inter-actions and weak face-to-face π-π stacking inter-actions [centroid-centroid distance = 3.8890 (6) Å] between the centroids of the pyrazole and phenyl rings are observed.
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