Related Experiment Video
Updated: May 18, 2026

Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
Published on: June 20, 2018
Evidence-based practice: reflux in sinusitis
Michael Lupa1, John M DelGaudio
1Department of Otolaryngology, Emory University Hospital Midtown, 550 Peachtree Street, 11th floor, Atlanta, GA 30308, USA.
Extraesophageal reflux, which affects areas above the esophagus, may play a role in sinusitis. Further research is needed to fully understand its impact on sinonasal diseases.
Area of Science:
- Otolaryngology
- Gastroenterology
Background:
- Extraesophageal reflux (EER) impacts the upper aerodigestive tract and lungs.
- The connection between EER and sinonasal conditions is under investigation.
Purpose of the Study:
- To explore the potential role of extraesophageal reflux in the pathophysiology of sinusitis and other sinonasal diseases.
Main Methods:
- Literature review of studies investigating reflux and sinonasal conditions.
Main Results:
- Growing evidence suggests a potential link between EER and sinonasal diseases.
- The exact contribution of reflux to sinusitis remains unclear.
Conclusions:
- Extraesophageal reflux may contribute to the development or exacerbation of sinusitis.
- Further research is warranted to elucidate the mechanisms and clinical significance.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
Tonsillitis II: Management
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
