Effect of arterial carbon dioxide on ventilation during recovery from impulse exercises of various intensities

To determine that whether arterial carbon dioxide (PaCO₂) affects ventilation (VE) during recovery from impulse-like exercises of various intensities, subjects performed four impulse-like tests with different workloads. Each test consisted of a 20-sec impulse-like exercise at 80 rpm and 60-min recovery. Blood samples were collected at rest and during recovery to measure blood ions and gases. VE was measured continuously during rest, exercise and recovery periods. A significant curvilinear relationship was observed between VE and pH during recovery from the 300- and 400-watt tests in all subjects. VE was elevated during recovery from the 100-watt test despite no change in any of the humoral factors. Arterialized carbon dioxide (PaCO₂) kinetics showed fluctuation, being increased at 1 min and decreased at 5 min during recovery, and this fluctuation was more enhanced with increase in exercise intensity. There was a significant relationship between VE and PaCO₂ during recovery from the 300- and 400-watt tests in all subjects. The results of the present study demonstrate that pH and neural factors drive VE during recovery from impulse-like exercise and that fluctuation in PaCO₂ controls VE as a feedback loop and this feedback function is more enhanced as the work intensity increases.