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Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
Published on: June 21, 2024
DC-gated high resolution three-dimensional lung imaging during free-breathing.
Stefan Weick1, Felix A Breuer, Philipp Ehses
1Department of Experimental Physics 5, University of Wuerzburg, Germany. sweick@physik.uni-wuerzburg.de
Journal of Magnetic Resonance Imaging : JMRI
|September 19, 2012
Summary
This study demonstrates how acquiring the k-space center signal (DC signal) in 3D FLASH MRI enables retrospective respiratory self-gating. This technique allows for high-resolution imaging of the entire human lung during free breathing.
Area of Science:
- Medical Imaging
- Magnetic Resonance Imaging (MRI)
- Pulmonary Imaging
Background:
- Free-breathing MRI of the lung is challenging due to respiratory motion.
- High spatial resolution imaging of the entire lung is desirable for comprehensive diagnosis.
Purpose of the Study:
- To implement and evaluate the k-space center signal (DC signal) acquisition for retrospective respiratory self-gating in a 3D FLASH sequence.
- To enable high-resolution imaging of the whole human lung during free breathing.
Main Methods:
- Volunteer and patient measurements were conducted under free-breathing conditions.
- The DC signal was acquired after image data acquisition within each excitation of a 3D FLASH sequence.
- The acquired DC signal was used to track respiratory motion for retrospective gating.
Main Results:
- The DC signal acquisition effectively extracts respiratory motion information for retrospective self-gating.
- This method allows for shorter echo times (TE).
- Shorter echo times lead to increased lung parenchyma signal-to-noise ratio (SNR).
Conclusions:
- Acquisition of the DC signal post-image acquisition enables successful retrospective gating.
- This technique facilitates the reconstruction of high-resolution images of the entire human lung.
- The method is suitable for free-breathing pulmonary MRI examinations.

