Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vein pattern recognition based on RGB images using Monte Carlo simulation and ridge tracking.

Journal of forensic sciences·2022
Same author

Validation of Zero TE-MRA in the Characterization of Cerebrovascular Diseases: A Feasibility Study.

AJNR. American journal of neuroradiology·2019
Same author

Type 2 diabetes mellitus reduces clinical complications and mortality in Stanford type B aortic dissection after thoracic endovascular aortic repair: A 3-year follow-up study.

Life sciences·2019
Same author

Plin3 protects against alcoholic liver injury by facilitating lipid export from the endoplasmic reticulum.

Journal of cellular biochemistry·2019
Same author

Expression of WD Repeat Domain 5 (WDR5) is Associated with Progression and Reduced Prognosis in Papillary Thyroid Carcinoma.

Medical science monitor : international medical journal of experimental and clinical research·2019
Same author

Occurrence, Removal and Bioaccumulation of Perfluoroalkyl Substances in Lake Chaohu, China.

International journal of environmental research and public health·2019

Related Experiment Video

Updated: Jul 12, 2026

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
02:09

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

RadiolGAN: Multicenter Feasibility Study of Synthetic CT From 3D Ultra-Short Echo Time MRI for Enhanced Pulmonary

Xi Zhu1,2, Wei Xia1, Xiaoliang Xie3

  • 1Department of Radiology, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu, China.

Journal of Magnetic Resonance Imaging : JMRI
|July 10, 2026
PubMed
Summary

RadiolGAN generates high-quality synthetic CT (sCT) from 3D ultrashort echo time (UTE) MRI, enhancing pulmonary visualization without radiation. This AI approach improves diagnostic confidence and image quality compared to traditional methods.

Keywords:
deep learninggenerative adversarial networklung imagingsynthetic CTultrashort echo time MRI

More Related Videos

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method
09:08

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method

Published on: December 20, 2024

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Related Experiment Videos

Last Updated: Jul 12, 2026

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
02:09

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method
09:08

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method

Published on: December 20, 2024

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Radiology

Background:

  • Chest CT uses ionizing radiation and requires breath-holding.
  • 3D ultrashort echo time (UTE) MRI offers radiation-free imaging but with suboptimal image quality.

Purpose of the Study:

  • Develop RadiolGAN, a deep learning model, to create synthetic CT (sCT) images from 3D UTE MRI.
  • Evaluate the efficacy of RadiolGAN-generated sCT for improved pulmonary visualization.

Main Methods:

  • Prospective, multicenter study involving 359 subjects across four centers.
  • Utilized 3 Tesla (3T) 3D UTE gradient-echo sequences.
  • Compared RadiolGAN-generated sCT with 3D UTE MRI and CycleGAN-generated sCT using quantitative metrics and radiologist assessments.

Main Results:

  • RadiolGAN-CT demonstrated superior signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and lower noise compared to 3D UTE.
  • RadiolGAN-CT achieved higher peak signal-to-noise ratio (PSNR), mean structural similarity index (MS-SSIM), and universal quality index (UQI) versus CycleGAN-CT.
  • Radiologists reported higher diagnostic confidence with RadiolGAN-CT compared to CycleGAN-CT and 3D UTE.

Conclusions:

  • RadiolGAN effectively generates high-fidelity synthetic CT images from 3D UTE MRI.
  • The developed method enhances pulmonary structure depiction and perceptual image similarity.
  • RadiolGAN represents a promising radiation-free alternative for chest imaging, improving diagnostic capabilities.