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Related Concept Videos

Structuralism01:26

Structuralism

Structuralism, an early psychological theory developed by Wilhelm Wundt and his student Edward Bradford Titchener, sought to dissect the human mind into its most fundamental components. Wundt's groundbreaking work in his laboratory set the stage for Titchener to define structuralism's goal as cataloging the "atoms" of the mind—sensations, images, and feelings—akin to how chemists identify elements of matter.
Titchener's approach to structuralism was unique. He employed introspection, a method...
Additional Subnuclear Structures02:10

Additional Subnuclear Structures

The eukaryotic nucleus is a double membrane-bound organelle that contains nearly all of the cell’s genetic material in the form of chromosomes. It is rightly called the “brain” of the cell as it shoulders the responsibility of responding to various physiological processes, stress, altered metabolic conditions, and other cellular signals. 
The nucleus contains many membrane-less subnuclear organelles or nuclear bodies, such as nucleoli, Cajal bodies, speckles, paraspeckles, etc. These nuclear...
Additional Subnuclear Structures02:10

Additional Subnuclear Structures

The eukaryotic nucleus is a double membrane-bound organelle that contains nearly all of the cell’s genetic material in the form of chromosomes. It is rightly called the “brain” of the cell as it shoulders the responsibility of responding to various physiological processes, stress, altered metabolic conditions, and other cellular signals. 
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Nomenclature of Secondary and Tertiary Amines01:12

Nomenclature of Secondary and Tertiary Amines

The secondary and tertiary amines are derivatives of ammonia, where two and three of its hydrogens are replaced by alkyl groups, respectively. Secondary and tertiary amines can be symmetrical with identical alkyl groups attached to the nitrogen atom or unsymmetrical when more than one type of alkyl group is present. The standard nomenclature of secondary and tertiary amines is similar to the names given to the primary amines. They are generally named alkylamines. As depicted in Figure 1, for...
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.

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Related Experiment Video

Updated: May 18, 2026

RNA Secondary Structure Prediction Using High-throughput SHAPE
13:42

RNA Secondary Structure Prediction Using High-throughput SHAPE

Published on: May 31, 2013

Super-secondary structure: a historical perspective.

Michael G Rossmann1

  • 1Department of Biological Sciences, Purdue University, West Lafayette, IN, USA. mr@purdue.edu

Methods in Molecular Biology (Clifton, N.J.)
|September 19, 2012
PubMed
Summary
This summary is machine-generated.

The evolution of protein folds reveals a limited set of structures that define protein domains. These protein folds are linked to specific functions, crucial for enzyme activity.

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Area of Science:

  • Structural Biology
  • Biochemistry
  • Molecular Biology

Background:

  • The concept of protein structure evolved from early ideas of super-secondary structures.
  • Understanding protein architecture is fundamental to deciphering biological function.

Observation:

  • A finite number of distinct protein folds have been identified.
  • These folds serve as the building blocks for individual protein domains.

Findings:

  • Each identified protein fold is typically associated with a specific biological function.
  • Enzyme active sites are often located at the interfaces between protein domains.

Implications:

  • This domain-based functional modularity aids in understanding complex biological processes.
  • Knowledge of protein folds and domains aids in protein engineering and drug design.