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Conceptual approaches to metastatic disease

M Seymour1

  • 1St James's Institute of Oncology, University of Leeds, Leeds, UK. M. Seymour@ncrn.org.uk

Annals of Oncology : Official Journal of the European Society for Medical Oncology
|September 19, 2012
PubMed
Summary

No abstract available in PubMed .

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Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Metastasis02:30

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