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Updated: May 18, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
[Leprosy-like cutaneous presentation of Histoplasma capsulatum infection in an African HIV+ patient]
Francesco Scarlata1, Claudia Imburgia, Marcello Trizzino
1Dipartimento di Scienze per la Promozione della Salute, Sezione di Malattie Infettive, Universita di Palermo, Palermo, Italy.
Abstract:
Histoplasma capsulatum is an opportunistic dimorphic fungus responsible for most often self-limiting or flu-like infections but potentially lethal in immunocompromised hosts. Histoplasmosis is rare in Europe. We reported a case of disseminated histoplasmosis in an African HIV patient with a leprosy-like primary cutaneous presentation and involvement of lungs, brain, limphnodes and eye. The therapy with liposomial B amphotericin and itraconazole led to a prompt resolution of the symptoms.
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