Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editor's Notebook: November 2024.

AJR. American journal of roentgenology·2025
Same author

Editor's Notebook: September 2024.

AJR. American journal of roentgenology·2025
Same author

Editor's Notebook: October 2024.

AJR. American journal of roentgenology·2025
Same author

Editor's Notebook: December 2024.

AJR. American journal of roentgenology·2025
Same author

Editor's Notebook: April 2025.

AJR. American journal of roentgenology·2025
Same author

Editor's Notebook: February 2025.

AJR. American journal of roentgenology·2025

Related Experiment Video

Updated: May 18, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Prostate cancer: multiparametric MRI for index lesion localization--a multiple-reader study.

Andrew B Rosenkrantz1, Fang-Ming Deng, Sooah Kim

  • 1Department of Radiology, New York University School of Medicine, Langone Medical Center, 560 First Ave, TCH-HW202, New York, NY 10016, USA. Andrew.Rosenkrantz@nyumc.org

AJR. American Journal of Roentgenology
|September 22, 2012
PubMed
Summary

Multiparametric MRI showed moderate accuracy in pinpointing prostate cancer

More Related Videos

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Related Experiment Videos

Last Updated: May 18, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Area of Science:

  • Radiology
  • Oncology
  • Uropathology

Background:

  • Accurate localization of prostate cancer's index lesion is crucial for effective treatment planning.
  • Multiparametric MRI (mpMRI) combines multiple imaging sequences to enhance lesion detection.

Purpose of the Study:

  • To assess the effectiveness of 3-T multiparametric MRI in localizing the primary tumor (index lesion) of prostate cancer before surgery.

Main Methods:

  • Fifty-one patients underwent pre-operative 3-T mpMRI (T2-weighted, diffusion-weighted, dynamic contrast-enhanced).
  • Six radiologists identified the most suspicious lesion region.
  • Uropathologists confirmed index lesion location from prostatectomy specimens using an 18-region scheme.

Main Results:

  • Pathology confirmed index lesions in 49 of 51 patients.
  • Exact-match sensitivity was 60.2% and PPV was 65.3%.
  • Approximate-match sensitivity improved to 75.9% and PPV to 82.6%.
  • Higher sensitivity was observed for more aggressive lesions (Gleason score > 6) and larger lesions (≥1 cm).
  • Lesion identification increased with the number of abnormal MRI parameters used.

Conclusions:

  • Multiparametric MRI offers moderate sensitivity and PPV for prostate cancer index lesion localization.
  • Diagnostic performance improves with higher Gleason scores and lesion size.
  • Utilizing multiple abnormal MRI parameters enhances localization accuracy.