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Updated: May 18, 2026

16:33
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
Published on: April 17, 2014
Directed patterning of the self-assembled silk-elastin-like nanofibers using a nanomechanical stimulus
Sara Johnson1, Young Koan Ko, Nitinun Varongchayakul
1Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
Abstract:
We investigate the effects of the frequency and density of a nanomechanical stimulus on nucleation and growth of silk-elastin-like protein polymer (SELP) nanofibers. Repetitive tappings are crucial to create nucleation areas and a potential molecular level mechanism was proposed. Using this technique mechanically guided nanofiber patterns were successfully created.

