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Related Concept Videos

Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
The Thyroid Gland01:23

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Goiter01:27

Goiter

Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...

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Updated: May 18, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
05:41

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions

Published on: February 9, 2024

Urticarial vasculitis reveals unsuspected thyroiditis.

Olga Ferreira1, Alberto Mota, Teresa Baudrier

  • 1Department of Dermatology and Venereology, Centro Hospitalar de São João EPE and Faculty of Medicine of Porto, Porto, Portugal. ocsferreira@gmail.com

Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica
|September 25, 2012
PubMed
Summary
This summary is machine-generated.

Urticarial vasculitis, a skin condition, was diagnosed in a patient with elevated antithyroid antibodies and subclinical thyroiditis. This highlights an uncommon association between these conditions.

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Last Updated: May 18, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
05:41

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Published on: February 9, 2024

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

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Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

Area of Science:

  • Dermatology
  • Immunology
  • Endocrinology

Background:

  • Urticarial vasculitis is characterized by skin lesions resembling urticaria but with vasculitic components.
  • It can be associated with infections, autoimmune diseases, and certain medications.

Observation:

  • A 38-year-old woman presented with generalized erythematous, violaceous plaques.
  • Skin biopsy confirmed leukocytoclastic vasculitis, leading to a diagnosis of urticarial vasculitis.
  • Initial laboratory tests were unremarkable, but antithyroid antibody titers were elevated.

Findings:

  • Thyroid ultrasound revealed features consistent with thyroiditis, despite normal thyroid function tests and no specific symptoms.
  • This suggests an underlying autoimmune process affecting the thyroid gland.
  • The patient was referred to endocrinology for further management.

Implications:

  • This case highlights an uncommon association between urticarial vasculitis and autoimmune thyroiditis.
  • Increased awareness of this association may aid in earlier diagnosis and management of related conditions.
  • Further research is warranted to elucidate the pathogenic mechanisms linking urticarial vasculitis and thyroiditis.