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Blood pressure and blood volume: acute and chronic considerations in hemodialysis

Michelle C Lewicki1, Peter G Kerr, Kevan R Polkinghorne

  • 1Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia.

Seminars in Dialysis
|September 26, 2012
PubMed

Insights

Hypertension is common and poorly controlled in dialysis patients. Managing blood volume is crucial for controlling blood pressure and reducing cardiovascular risks in this population.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Internal Medicine

Background:

  • Hypertension is highly prevalent and poorly controlled in dialysis patients, increasing morbidity and mortality.
  • Expanded extracellular volume is a significant risk factor for adverse outcomes in dialysis patients.
  • Current dialysis practices often result in chronic volume expansion.

Purpose of the Study:

  • To review the critical relationship between blood volume and hypertension in dialysis patients.
  • To explore potential management targets for optimizing volume status and blood pressure control.

Main Methods:

  • This is a review article, synthesizing existing literature.
  • Focuses on the role of blood volume in hypertension pathogenesis in dialysis.
  • Examines challenges in managing blood pressure and volume state.

Main Results:

  • Blood volume expansion is a key factor in dialysis-related hypertension.
  • Effective volume management is essential for minimizing hemodynamic instability during dialysis.
  • Controlling volume status aids in preserving cardiac structure and function.

Conclusions:

  • Optimizing blood volume management is critical for improving hypertension control in dialysis patients.
  • Addressing volume expansion may mitigate cardiovascular risks and improve patient outcomes.
  • Further research is needed to guide evidence-based management strategies.

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