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Updated: May 18, 2026

Structural Characterization of Mannan Cell Wall Polysaccharides in Plants Using PACE
Published on: October 16, 2017
Gastroprotective effect and structure of a rhamnogalacturonan from Acmella oleracea
Adamara M Nascimento1, Lauro M de Souza, Cristiane H Baggio
1Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, CEP 81.531-980, CP 19046, Curitiba, PR, Brazil.
Abstract:
The plant Acmella oleracea (L.) R.K.Jansen (Asteraceae), locally known as jambu, is widely used in Legal Amazon in local dishes and in folk medicine. A polysaccharide (SC) was isolated from this plant, following aqueous extraction, which contained uronic acid, galactose, arabinose, rhamnose, and glucose in a 15:2:1:1:0.5 molar ratio and had a M(w) 226,000 g/mol. Methylation analysis and NMR spectroscopy indicated that SC is a rhamnogalacturonan composed of a long chain of →4)-6-OMe-α-D-GalpA-(1→, interspersed with some α-L-Rhap residues, partly substituted by side-chains of type II arabinogalactans. SC significantly inhibited ethanol-induced gastric ulcers in rats with an ED₅₀ of 1.5 mg/kg, indicating that SC acts as gastroprotective agent.
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