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Related Experiment Video

Updated: May 18, 2026

Optogenetic Perturbation of Neural Activity with Laser Illumination in Semi-intact Drosophila Larvae in Motion

Optogenetic Perturbation of Neural Activity with Laser Illumination in Semi-intact Drosophila Larvae in Motion

Published on: July 4, 2013

Optogenetics: eye movements at light speed.

Matthew W Self¹, Pieter R Roelfsema

¹Department of Vision & Cognition, The Netherlands Institute for Neurosciences, Meibergdreef 47, 1105BA, Amsterdam, The Netherlands.

Current Biology : CB

|September 29, 2012

Summary

This summary is machine-generated.

Scientists used optogenetics to activate specific neurons in monkeys, successfully speeding up their task performance. This breakthrough demonstrates optogenetics

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Area of Science:

Neuroscience
Primate research
Optogenetics

Background:

Optogenetics offers precise control over neuronal activity but has faced challenges in non-human primates.
Previous attempts to modulate complex behaviors via optogenetics in primates were limited.

Purpose of the Study:

To investigate the feasibility of using optogenetics to modulate behavior in primates.
To determine if targeted neuronal activation in the frontal cortex can alter cognitive task performance.

Main Methods:

Researchers employed optogenetic techniques to selectively activate neurons in the frontal cortex of monkeys.
Behavioral tasks were designed to measure performance changes following neuronal stimulation.

Main Results:

Successful activation of targeted neurons in the monkey frontal cortex using light.
Demonstrated a significant acceleration in task performance after neuronal activation.

Conclusions:

Optogenetics can be effectively used to alter behavior in primates.
Targeted neuronal activation in the frontal cortex is a viable strategy to enhance cognitive performance.