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Preliminary study of an intestinal bio-robot system based on nerve stimulation
Lan Zhu1, Hongying Liu, Zhenyu Wang
1Key Laboratory of Biorheological Science and Technology of Ministry of Education, College of Bioengineering of Chongqing University, Chongqing 400044, PR China.
Background:
Wireless capsule endoscopes for diagnosis and treatment in the gastrointestinal tract face the common problem of active actuation. To tackle this difficulty, a non-invasive intestinal bio-robot system with active actuation based on nerve stimulation was developed.
Methods:
This intestinal inspection system utilized a natural organism--the mud eel--to serve as the locomotion mechanism, and it was controlled by a LabVIEW-programmed pulse generator. The exterior control unit was able to actively drive and remotely control the navigation and site-specific anchoring of the organism.
Results:
Through in vitro stimulation experiments, a method of controlling the organism's forward motion was obtained: when the organism was stimulated at the tail, it moved forward at a relatively fast speed and with high repeatability. The stimulator parameters were as follows: amplitude 1.85 μA, frequency 2 Hz, pulse duration 500 μs.
Conclusions:
Since this is a preliminary study, considerable work remains to be done. However, the results could provide a solid theoretical basis for further research toward producing a practical intestinal bio-robot for the diagnosis and treatment of the gastrointestinal tract.
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