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Updated: May 18, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
Scars after second intention healing.
Matthew R Donaldson1, Brett M Coldiron
1Department of Mohs Micrographic Surgery and Cutaneous Oncology, Mountain West Dermatology, Grand Junction, Colorado. mrdonaldson@medscape.com
Second intention healing (SIH) offers a cost-effective, low-morbidity option for skin cancer defects. Facial location significantly impacts cosmetic outcomes, with certain areas healing better than others.
Area of Science:
- Dermatology
- Plastic Surgery
- Wound Healing
Background:
- Second intention healing (SIH) is a valuable technique for managing defects after skin cancer removal.
- It offers benefits such as reduced intraoperative morbidity and lower procedure costs.
- SIH is associated with low rates of infection, pain, and bleeding, simplifying wound care.
Purpose of the Study:
- To review the literature on SIH based on facial anatomy.
- To understand how anatomical location influences cosmetic outcomes of SIH.
- To highlight the advantages and potential complications of SIH.
Main Methods:
- Literature review focusing on SIH and facial anatomy.
- Categorization of facial regions into concavities (NEET), convexities (NOCH), and flat areas (FAIR).
- Analysis of cosmetic outcomes based on defect location.
Main Results:
- Cosmetic outcomes of SIH are highly dependent on the anatomical location of the defect.
- Concave facial areas (e.g., medial canthus, conchal bowl) often heal imperceptibly.
- Convex surfaces (e.g., nasal tip, malar cheek) may result in poor healing and depressed scars, while flat areas show unpredictable cosmesis.
Conclusions:
- SIH is a viable reconstructive option after skin cancer excision, with location being a critical factor for cosmetic results.
- Understanding facial topography (NEET, NOCH, FAIR) aids in predicting SIH outcomes.
- Surgeons should consider SIH as part of their reconstructive algorithm, being aware of potential complications like exuberant granulation or scar distortion.
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