Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

Longitudinal Research

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Use of Virtual Reality-Reminiscence Interventions in Older Adults Living With Dementia or Cognitive Impairment: An Integrative Review.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society·2026

Same author

The Effectiveness of Reminiscence Interventions on Depression and Depressive Symptoms in Community-dwelling Older Adults without Significant Cognitive Impairment: A Systematic Review.

Western journal of nursing research·2025

Same author

Reduced Readmission and Increased Patient Satisfaction in Post-Cardiac Arrhythmia Ablation: A Randomized Pilot Study.

Journal of nursing care quality·2023

Same author

The mediating role of religion and loneliness on the association between reminiscence functions and depression: a call to advance older adults' mental health.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society·2023

Same author

Transcultural adaptation in translating measurement instruments: Challenges and learned lessons.

International journal of nursing knowledge·2023

Same author

Outcomes From an Interprofessional Geriatric Outreach and Training Program.

Innovation in aging·2022

Search research articles

Related Experiment Video

Updated: May 18, 2026

Oral Health Assessment by Lay Personnel for Older Adults

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Engaging students in gerontological research.

Juliette Shellman¹

¹School of Nursing, University of Connecticut, Storrs, Connecticut 06296-2026, USA. juliette.shellman@uconn.edu

Journal of Gerontological Nursing

|October 3, 2012

Summary

Preparing nursing students for gerontological nursing research is crucial. The Students Advancing Reminiscence Research (STARR) program effectively engages students in research, benefiting both students and faculty.

Area of Science:

Gerontological Nursing
Nursing Education Research

Background:

Nursing educators face challenges balancing teaching, scholarship, and service, hindering student research engagement.
There is a critical need to prepare nursing students for active roles in gerontological nursing research.

Purpose of the Study:

To describe the impetus for creating the Students Advancing Reminiscence Research (STARR) program.
To present implications and recommendations for nursing education, practice, and policy regarding gerontological nursing research.

Main Methods:

The STARR program is an innovative approach to foster student engagement in research.
It utilizes available resources to enhance faculty research programs.

Main Results:

More Related Videos

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

Related Experiment Videos

Last Updated: May 18, 2026

Oral Health Assessment by Lay Personnel for Older Adults

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

The STARR program successfully engages students in gerontological nursing research.

It provides a model for integrating research into nursing education.

Conclusions:

Innovative programs like STARR are essential for preparing future gerontological nurses.
Recommendations are provided for advancing gerontological nursing research through education, practice, and policy.