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Updated: May 18, 2026

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Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents
Published on: May 1, 2012
A multifunctional nanosensor based on silica nanoparticles and biological applications in living cells
Wenyu Wu1, Zhihong Sun, Ye Zhang
1Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China.
Abstract:
A multifunctional nanosensor based on silica nanoparticles has been designed by importing metal binding sites and hydrogen bonds directly attached to the chromophore. It works well in the recognition of Hg(2+), H(2)PO(4)(-), S(2-)via different combination mechanisms, and intracellular imaging.

