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Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene
Published on: December 31, 2014
Cell transformation assays
1New York University School of Medicine, New York, New York, USA.
Current Protocols in Toxicology
|October 10, 2012
Abstract:
Morphological transformation of mammalian cells following exposure to a chemical agent is frequently used as a preliminary screen for the carcinogenic potential of the agent. This unit describes a protocol using Syrian hamster embryo (SHE) cells to assay transformation.
