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Prazosin-induced stress incontinence.
1Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.
Obstetrics and Gynecology
|March 1, 1990
Summary
Genuine stress incontinence caused by the antihypertensive drug prazosin can resolve by switching medications. Urodynamic studies confirmed improved urethral function after discontinuing prazosin, highlighting medication review for such cases.
Area of Science:
- Pharmacology
- Urology
- Internal Medicine
Background:
- Prazosin, an alpha-1 adrenergic receptor antagonist, is widely used for hypertension.
- Alpha-blockers can relax the bladder neck and urethra, potentially causing urinary incontinence.
- Stress urinary incontinence (SUI) is a common condition, particularly in women.