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Updated: May 17, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis triggered by tetanus-diphtheria vaccination.
Vasco Coelho Macias1, Daniela Cunha
1Department of Dermatology and Venereology, Hospital de Curry Cabral, Lisbon, Portugal. vmcmacias@gmail.com
Cutaneous and Ocular Toxicology
|October 12, 2012
Summary
Psoriasis, a common inflammatory skin condition, can have various triggers. This case study details the first instance of psoriasis being triggered by the tetanus and diphtheria (Td) vaccine.
Area of Science:
- Immunology
- Dermatology
- Vaccinology
Background:
- Psoriasis is a prevalent chronic inflammatory dermatosis.
- Multiple external and internal factors are known to trigger psoriasis flares.
- Immunization is a common medical intervention with potential side effects.
Observation:
- A case report of a patient experiencing psoriasis onset following tetanus and diphtheria immunization (Td vaccine).
Findings:
- This represents the first documented case linking the Td vaccine to psoriasis development.
- The study highlights a potential, previously unreported adverse effect of the Td vaccine.
Implications:
- Suggests a need for further investigation into vaccine-induced immune responses in susceptible individuals.
- May inform clinical practice regarding patient screening and post-vaccination monitoring for psoriasis.
- Contributes to understanding the complex interplay between immunization and autoimmune conditions.
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