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Updated: May 17, 2026

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
Published on: August 1, 2018
Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells
Michael D Scott1, Rinku Dutta, Manas K Haldar
1Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58108-6050, USA. sanku.mallik@ndsu.edu
Abstract:
Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.

