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Updated: May 17, 2026

Studying Murine Small Bowel Mechanosensing of Luminal Particulates
Published on: March 18, 2022
Sonographic demonstration of human small intestinal migrating motor complex phase III
C J Liu1, S C Huang, Y C Huang
1Department of Internal Medicine, Mackay Memorial Hospital, Taitung Branch, Taitung, Taiwan.
Background:
Migrating motor complex phase III (MMC phase III) of intestine is an important physiological mechanism traditionally recognized by myoelectric recordings or pressure tracings. Direct imaging is difficult and sonographic visualization in human has not been reported.
Methods:
We have demonstrated this unique phenomenon in three patients who underwent abdominal sonographic examinations. Characteristic images were recorded by videotape and both spatial and temporal features were analyzed.
Key Results:
Occurrences of multiple equally spaced, rhythmic intestinal contractions were observed. Parameters including wave frequency, propagation velocity, and duration of the events agreed with those of the well-known phase III. The presence of distinct cyclic patterns observed in two and abolition by meal in the other patient further support our conclusion.
Conclusions & Inferences:
We conclude that the migrating waves observed in our study represent the human MMC phase III. This unique finding in human subjects merits further investigation.
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