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A ligation-triggered highly sensitive fluorescent assay of adenosine triphosphate based on graphene oxide
Wenping Zhu1, Ziwei Zhao, Zhen Li
1State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
The Analyst
|October 20, 2012
Abstract:
A simple, amplification-free and sensitive fluorescent biosensor for ATP detection was developed based on the ATP-dependent enzymatic reaction (ATP-DER) and the different adsorption affinity between graphene oxide (GO) and DNA structures. The proposed method was simple and convenient and also showed high sensitivity and selectivity to ATP.
