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Related Concept Videos

Introduction to Psychological Disorders01:19

Introduction to Psychological Disorders

Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Theoretical Approaches to Psychological Disorder01:29

Theoretical Approaches to Psychological Disorder

The development of psychological disorders, which are characterized by deviant, maladaptive, and personally distressing behaviors, has been explored through several theoretical approaches.
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...

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Related Experiment Video

Updated: May 17, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Is mental illness complex? From behavior to brain.

Albert C Yang1, Shih-Jen Tsai

  • 1Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan. accyang@gmail.com

Progress in Neuro-Psychopharmacology & Biological Psychiatry
|October 24, 2012
PubMed
Summary
This summary is machine-generated.

Mental illness may stem from a loss of brain complexity. This study explores quantifying order and randomness in behavior and neuronal activity to understand mental disorders.

Keywords:
BOLDComplexityEEGEntropyMEGMSEMental illnessSpontaneous brain activityblood oxygen level dependentelectroencephalogramfMRIfunctional magnetic resonance imagingmagnetoencephalographymultiscale entropy

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Area of Science:

  • Neuroscience
  • Complexity Science
  • Psychiatric Medicine

Background:

  • The human brain's complexity enables adaptation and mental functions, but this adaptability is impaired in mental illness.
  • Abnormal behaviors in mental illness present challenges in quantification and classification.
  • Existing complexity science concepts are often inaccessible to clinicians and neuroscientists.

Purpose of the Study:

  • To introduce accessible applications of complexity science methods for studying mental illness.
  • To propose a framework for understanding mental illness as a loss of brain complexity.
  • To link macroscopic behavioral changes with microscopic neuronal activity.

Main Methods:

  • Applying complexity science concepts to analyze human behavior and neuronal activity.
  • Quantifying the order and randomness of dynamic macroscopic human behavior.
  • Quantifying the order and randomness of dynamic microscopic neuronal activity.

Main Results:

  • Mental illness is proposed as a loss of brain complexity.
  • A framework is suggested for studying mental illness by quantifying order and randomness.
  • The need for linking macroscopic behaviors to microscopic neuronal dynamics is highlighted.

Conclusions:

  • Understanding mental illness requires quantifying brain complexity.
  • Complexity science offers valuable tools for psychiatric research.
  • Further research is needed to bridge the gap between behavior and neuronal dynamics.