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Updated: May 17, 2026
09:07
Single-Step Enrichment of a TAP-Tagged Histone Deacetylase of the Filamentous Fungus Aspergillus nidulans for Enzymatic Activity Assay
Published on: May 1, 2019
A fluorescent probe for detection of histone deacetylase activity based on aggregation-induced emission
Koushik Dhara1, Yuichiro Hori, Reisuke Baba
1Graduate School of Engineering, Osaka University, Osaka 565-0871, Japan.
Chemical Communications (Cambridge, England)
|October 25, 2012
Abstract:
A tetraphenylethylene-derivative fluorescent probe for the one-step detection of histone deacetylases (HDAC) was developed. The deacetylation of the probe triggers electrostatic interaction between the molecules and automatically leads to fluorescence enhancement based on aggregation-induced emission (AIE).
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