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Cerebral Ischemic Coma Model Induced by Modified Four-Vessel Occlusion

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Coma blisters sans coma.

Silke Heinisch¹, Michael Loosemore, Carrie A Cusack

¹Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

|October 26, 2012

Summary

This summary is machine-generated.

Coma blisters, typically seen in unconscious patients, were diagnosed in a conscious woman. Histopathology confirmed eccrine gland necrosis, a key indicator of these skin lesions.

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Area of Science:

Dermatology
Pathology

Background:

Coma blisters (CBs) are typically associated with unconscious states, often induced by barbiturates.
These self-limited lesions characteristically occur in pressure-exposed areas.

Observation:

A case of CBs was observed in a 41-year-old woman who presented with tense abdominal bullae and erythema after a transatlantic flight.
Notably, the patient was fully conscious and had no reported medication use or prior medical history.

Findings:

The clinical diagnosis of CBs was histopathologically confirmed.
Key findings included eccrine gland necrosis, a definitive characteristic of these bullous lesions.

Implications:

This case expands the clinical presentation of Coma Blisters beyond unconscious states.
Highlights the importance of considering CBs in conscious individuals presenting with unexplained bullous lesions.
Eccrine gland necrosis serves as a crucial diagnostic marker for CBs, irrespective of patient consciousness.