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09:01
The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques
Published on: July 3, 2014
Nose and lungs: one way, one disease
Davide Caimmi1, Alessia Marseglia, Giovanni Pieri
1Department of Pediatrics of the University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. davide.caimmi@gmail.com
Italian Journal of Pediatrics
|October 27, 2012
Summary
Pediatric asthma, allergic rhinitis, and rhinosinusitis are linked. Treating nasal conditions can improve asthma control and reduce airway hyperresponsiveness, highlighting a common pathogenic basis.
Area of Science:
- Pediatric Allergy and Immunology
- Otolaryngology
- Respiratory Medicine
Background:
- Asthma, allergic rhinitis, and rhinosinusitis are common pediatric conditions.
- These diseases are increasingly viewed as manifestations of a shared pathogenic process.
- The respiratory tract's anatomical and functional unity supports this interconnectedness.
Purpose of the Study:
- To analyze the clinical and pathogenic links between asthma and sinusitis in children.
- To explore the therapeutic implications of managing these interconnected respiratory diseases.
- To emphasize the importance of evaluating for concomitant nasal conditions in pediatric asthma patients.
Main Methods:
- Review of current scientific literature on asthma, allergic rhinitis, and rhinosinusitis.
- Analysis of clinical observations regarding the interplay between upper and lower airway diseases.
- Examination of treatment strategies for nasal conditions and their impact on asthma.
Main Results:
- Treatments for nasal diseases show promise in enhancing asthma control.
- Medications targeting rhinitis and sinusitis can reduce bronchial hyperresponsiveness.
- Occult sinusitis may be a factor in difficult-to-treat pediatric asthma cases.
Conclusions:
- A common pathogenic mechanism likely underlies asthma, allergic rhinitis, and rhinosinusitis in children.
- Integrated management strategies addressing both nasal and airway diseases are crucial.
- Evaluating for nasal pathology is essential in pediatric asthma, particularly in refractory cases.
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