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Rab Proteins01:14

Rab Proteins

Rab proteins constitute the largest family of monomeric GTPases, of which 70 members are present in humans. Rab proteins and their effectors regulate consecutive stages of vesicle transport such as vesicle transport, docking, and fusion to the correct recipient membrane.
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Related Experiment Video

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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
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Published on: August 18, 2023

[Rabies in Poland in 2010].

Małgorzata Sadkowska-Todys1, Bozena Kucharczyk

  • 1Zakład Epidemiologii, Narodowego Instytutu Zdrowia Publicznego - Państwowego Zakładu Higieny w Warszawie. mtodys@pzh.gov.pl

Przeglad Epidemiologiczny
|October 30, 2012
PubMed
Summary

Rabies cases in Poland increased in 2010, particularly in terrestrial animals, but the overall situation remains controlled due to oral vaccination programs. The number of people vaccinated after potential exposure to rabies is decreasing.

Area of Science:

  • Veterinary Epidemiology
  • Zoonotic Disease Surveillance
  • Public Health

Context:

  • Rabies remains a significant public health concern globally.
  • Poland has implemented control measures, including oral vaccination of wild animals since 1993.
  • Monitoring the epidemiological situation is crucial for assessing the effectiveness of these interventions.

Purpose:

  • To evaluate the epidemiological status of rabies in Poland during 2010.
  • To analyze rabies cases in animals and human exposures.
  • To assess trends in rabies post-exposure prophylaxis.

Summary:

  • In 2010, Poland reported 152 animal rabies cases, with a notable increase in Małopolskie voivodship. Terrestrial animals, especially foxes, were frequently implicated in human exposures.

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  • A total of 7,243 individuals received rabies vaccinations, with the majority following exposure to animals where rabies could not be ruled out.
  • Despite localized increases, a long-term decreasing trend in rabies is observed, attributed to successful oral vaccination campaigns for wild animals.

    • Impact:

    • The findings indicate the continued effectiveness of rabies control strategies in Poland.
    • The study highlights the importance of ongoing surveillance for both animal and human cases.
    • Results support the sustained implementation of public health measures to manage zoonotic diseases.