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Activation of innate immunity is required for efficient nuclear reprogramming

Jieun Lee1, Nazish Sayed, Arwen Hunter

  • 1Division of Cardiovascular Medicine, Stanford University, CA 94305, USA.

Cell
|October 30, 2012
PubMed
Summary

Scientists found that activating the toll-like receptor 3 (TLR3) pathway enhances the efficiency of inducing pluripotency using viral or messenger RNA (mRNA) delivery methods for reprogramming factors.

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