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Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...
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The hyoid bone is a small U-shaped bone located in the upper neck at the level of the inferior mandible, with its tips pointing posteriorly. It does not directly articulate with any other bone in the body. The hyoid acts as the attachment site for the tongue, the larynx, and the pharynx. It is held in position by a series of small muscles attached from above or below. These muscles help to move the hyoid up/down or forward/back in coordination with movements of the tongue, larynx, and pharynx...
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Updated: May 17, 2026

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights
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Published on: October 13, 2023

Massively enlarged styloid process presenting as a submandibular mass.

Lorna Elizabeth Langstaff1, Tarik Abed, Jonathan Philpott

  • 1Department of ENT, York Teaching Hospital NHS Foundation Trust, York, UK. lorna.langstaff@doctors.org.uk

BMJ Case Reports
|October 30, 2012
PubMed
Summary

A 47-year-old man experienced persistent submandibular swelling and pain. Surgical removal of an enlarged styloid process resolved his symptoms, offering a successful treatment for Eagle syndrome.

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Area of Science:

  • Otolaryngology
  • Head and Neck Surgery
  • Anatomy

Background:

  • Eagle syndrome is a rare condition characterized by elongation of the styloid process.
  • Symptoms can include facial pain, dysphagia, and neck pain, often mimicking other conditions.
  • Submandibular swelling and pain are atypical presentations of Eagle syndrome.

Observation:

  • A 47-year-old male presented with a 6-month history of left submandibular swelling and pain.
  • Initial investigations were inconclusive.
  • Computed tomography (CT) imaging of the neck revealed a significantly enlarged styloid process.

Findings:

  • The enlarged styloid process was identified as the cause of the patient's symptoms.
  • Surgical excision of the elongated styloid process and stylohyoid ligament was performed.
  • Histopathological examination confirmed the diagnosis.

Implications:

  • Surgical intervention is an effective treatment for symptomatic Eagle syndrome.
  • Prompt diagnosis and management can lead to complete symptom resolution and improved quality of life.
  • This case highlights the importance of considering anatomical abnormalities in the differential diagnosis of persistent head and neck pain.