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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Association between periodontitis and gestational diabetes mellitus: a case-control study
Rafael Paschoal Esteves Lima1, Luís Otávio Miranda Cota, Fernando Oliveira Costa
1Department of Periodontology, Dentistry School, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Journal of Periodontology
|October 31, 2012
Summary
This study found no association between periodontitis and gestational diabetes mellitus (GDM) in pregnant women. However, maternal age, chronic hypertension, and BMI were significant risk factors for GDM.
Area of Science:
- Obstetrics and Gynecology
- Periodontology
- Public Health
Background:
- Previous research suggests a link between gestational diabetes mellitus (GDM) and periodontitis.
- This study investigates the potential association and GDM risk factors.
Purpose of the Study:
- To analyze the association between periodontitis and GDM.
- To identify risk variables associated with GDM.
Main Methods:
- A case-control study involving 360 women (90 GDM, 270 controls).
- Periodontal examinations included bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL).
- Periodontitis defined as ≥4 teeth with PD ≥4 mm, CAL ≥3 mm, and BOP; logistic regression used to analyze GDM risk factors.
Main Results:
- Periodontitis prevalence was 40% in GDM cases and 46.3% in controls.
- No significant association was found between periodontitis and GDM (OR = 0.74; 95% CI = 0.40–1.38).
- Significant GDM risk factors included maternal age (OR = 2.65), chronic hypertension (OR = 3.16), and BMI (OR = 1.99).
Conclusions:
- High periodontitis prevalence observed in both GDM and control groups.
- No association between periodontitis and GDM was identified.
- Recommends implementing health policies for pregnant women's periodontal care.
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