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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
Published on: August 18, 2023
[Human rabies in Abidjan (Côte d'Ivoire): recent cases]
S I Ouattara1, H Cissé, G Kouakou
1Service de Maladies Infectieuses et Tropicales du CHU de Treichville, 01 BPV 3 Abidjan 01, Abidjan, Côte d'Ivoire. si_ouattara@yahoo.fr
Human rabies is a serious threat, especially from stray dogs. Increased public awareness, dog vaccination, and stray dog control are crucial for prevention in Ivory Coast.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Context:
- Human rabies cases present significant public health challenges.
- Treichville University Hospital Center serves as a key facility for infectious disease treatment in Ivory Coast.
Purpose:
- To detail the epidemiological and clinical characteristics of human rabies cases.
- To analyze trends and outcomes of human rabies at a major hospital center.
Summary:
- Seven human rabies cases were documented between 2005-2009, predominantly from stray dog bites.
- Incomplete post-exposure prophylaxis and lack of pre-exposure vaccination were noted in all patients.
- Furious rabies symptoms appeared after a mean of 47.7 days post-bite, leading to death within a mean of 4.7 days.
Impact:
- Highlights critical gaps in rabies prevention strategies, including vaccination and stray animal management.
- Underscores the urgent need for enhanced public awareness campaigns regarding rabies transmission and prophylaxis.
- Informs public health policy for rabies control in Ivory Coast and similar regions.
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