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Updated: May 17, 2026

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Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
Massive bone loss: allograft-prosthetic composites and beyond.
1Rush University Medical Center, 1620 West Harrison Avenue, Chicago, Illinois 60612, USA. robmayle@gmail.com
The Journal of Bone and Joint Surgery. British Volume
|November 3, 2012
Summary
Revision total hip arthroplasty (THA) is increasing, posing challenges for femur reconstruction. This review examines treatment options for severe femoral defects in revision THA.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
Background:
- Revision total hip arthroplasty (THA) is projected to rise significantly, increasing the complexity of femur reconstruction.
- Massive bone loss in the femur presents a substantial surgical challenge during revision THA procedures.
Purpose of the Study:
- To review treatment options for severe femoral defects (Paprosky types IIIb and IV) in revision THA.
- To analyze the outcomes associated with various reconstructive techniques for compromised femurs.
Main Methods:
- Literature review of surgical techniques for severe femoral defects in revision THA.
- Analysis of outcomes for options including resection arthroplasty, allograft prosthetic composite (APC), proximal femoral replacement, cementless modular tapered fluted stems, and impaction grafting.
Main Results:
- The study evaluates multiple reconstructive strategies for complex femoral defects.
- Outcomes data for severe femoral defects (Paprosky types IIIb and IV) are presented for each treatment option.
Conclusions:
- Effective reconstruction of femurs with massive bone loss is crucial for successful revision THA.
- Understanding the outcomes of different surgical options is essential for managing severe femoral defects in revision hip surgery.
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