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Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

Porous silicon biosensor: current status.

Saakshi Dhanekar¹, Swati Jain

¹Jamia Millia Islamia (Central University), Jamia Nagar, New Delhi 110025, India. saakshi.dhanekar@yahoo.com

Biosensors & Bioelectronics

|November 6, 2012

Summary

This summary is machine-generated.

Nano-porous silicon (PS) is a versatile material for developing advanced biosensors. This review explores PS fabrication and its application in detecting various analytes using different methodologies.

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Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

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Published on: September 19, 2017

Area of Science:

Materials Science
Biotechnology
Nanotechnology

Background:

Biosensing technologies are crucial for modern diagnostics and point-of-care applications.
Developing highly sensitive, stable, and low-cost biosensors requires extensive research.
Nano-porous silicon (PS) has emerged as a promising substrate for biosensor fabrication due to its unique properties.

Purpose of the Study:

To review the fabrication of nano-porous silicon (PS).
To explore the biosensing capabilities of PS for detecting diverse analytes.
To discuss various detection methodologies and performance metrics of PS-based biosensors.

Main Methods:

Fabrication of nano-porous silicon (PS) substrates.
Immobilization of biomolecules onto PS surfaces.
Detection of analytes using electrical, electrochemical, optical, and label-free techniques.

Main Results:

PS exhibits tunable optico-physico properties, tailored morphology, and versatile surface chemistry.
PS-based biosensors have demonstrated capabilities for detecting glucose, DNA, antibodies, bacteria, and viruses.
Various methodologies show promising performance for PS-based biosensing applications.

Conclusions:

Nano-porous silicon (PS) is a highly promising transducer material for advanced biosensor development.
Further research is needed to address challenges and explore future prospects of PS-based biosensors.
PS offers a tunable platform for sensitive and selective detection of a wide range of analytes.