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Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Percutaneous renal cryoablation after partial nephrectomy: technical feasibility, complications and outcomes
Ryan M Hegg1, Grant D Schmit, Stephen A Boorjian
1Department of Radiology, Mayo Clinic School of Medicine, Rochester, Minnesota 55905, USA.
The Journal of Urology
|November 6, 2012
Summary
Percutaneous renal cryoablation is a safe and effective minimally invasive treatment for kidney tumors recurring after partial nephrectomy. This technique demonstrates good short-term results with low complication rates and preserved kidney function.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Oncology
Background:
- Treatment of recurrent or de novo renal tumors after partial nephrectomy presents a clinical challenge.
- Percutaneous renal cryoablation offers a minimally invasive therapeutic option.
Purpose of the Study:
- To evaluate the technical feasibility, complication rates, and outcomes of percutaneous renal cryoablation for ipsilateral renal tumors post-partial nephrectomy.
- To assess oncologic outcomes and renal function preservation in patients undergoing this procedure.
Main Methods:
- Retrospective review of 48 patients with 68 ipsilateral renal tumors treated with percutaneous cryoablation between March 2003 and January 2012.
- Evaluation of oncologic outcomes, complications (Clavien-Dindo classification), and renal function (estimated glomerular filtration rate).
Main Results:
- All procedures were technically successful; median tumor size was 2.5 cm.
- Local tumor recurrence occurred in 9.3% of cases with biopsy-proven or suspected renal cell carcinoma.
- Major complications (grade ≥3) occurred in 5.7% of procedures, with no perioperative deaths. Median GFR change was -1.5 ml/min.
Conclusions:
- Percutaneous renal cryoablation is a technically feasible option for treating renal tumors after ipsilateral partial nephrectomy.
- The procedure is associated with a low rate of major complications and acceptable short-term oncologic outcomes.
- Renal function is relatively preserved, making it a viable option for this challenging patient group.
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