Related Experiment Video
Updated: May 17, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Giant atrial thrombus presenting as a tumor
N Nicolaou1, A Becker, G Mc Michael
1Division of Cardiothoracic Surgery, Flora Clinic, Johannesburg, South Africa.
Introduction:
Right Atrial masses may represent tumors or thrombi of the heart and are potentially fatal if left untreated.
Presentation Of Case:
A 45-year-old woman with a previous history of breast cancer who was found to have a right atrial mass diagnosed as a tumor by Echocardiography and Computed Tomography which ultimately proved to be a giant organized thrombus at surgery.
Discussion:
Metastatic tumors of the heart are 20 times more common than primary tumors and malignancies that often involve the heart include breast, lung, lymphoma, melanoma and sarcomas. Myxomas remain the most common cause of atrial tumors and are classically described arising on the left but a significant amount do occur on the right side. Presenting features with masses in the right atrium are similar to patients with tricuspid stenosis which may present with tiredeness, swelling of the feet, hepatomegaly and ascites. The clinical presentation and history may be of help in the diagnosis especially if the patient has a confirmed tumour.
Conclusion:
Despite our current state of the art equipment these "masses" still pose a diagnostic challenge in distinguishing between solid thrombus and tumour as to determine the appropriate therapeutic approach. Surgical removal of Giant Atrial Thrombi appears to be the procedure of Choice.
Related Concept Videos
Venous Thrombosis I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis III: Interprofessional Care