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Updated: May 17, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
Published on: January 7, 2018
[Impaired fasting glycaemia as a risk factor of coronary heart disease]
Abstract:
The aim of the research was to study the prevalence of early carbohydrate metabolism disorders and their relationship to coronary heart disease (CHD) risk factors (RF) in the female population. Epidemiological studies were carried out on 952 women aged 20-59 years. The frequency of impaired fasting glycaemia (IFG) was 4,6 %, and the impaired glucose tolerance (IGT) found only 0,2%. It was found that the prevalence of CHD in female population is found in 2 times more often in the presence of IFG than in its absence (40,0% and 23,2 %, respectively), observed in almost all age groups except 20-29 years, where CHD totally absent in individuals with IFG. The detection rate of the RF of cardiovascular disease with and without IFG also somewhat different: for example, hypertension, hypertriglyceridemia, hypercholesterolemia, obesity, is the criterion of the presence of metabolic syndrome, met with greater frequency in the presence of IFG.
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