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Updated: May 17, 2026
08:38
A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy
Published on: April 30, 2015
Morphology of liver.
Madhur Gupta1, Lavina Sodhi, T D Yadav
1Department of Anatomy, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
The Indian Journal of Surgery
|November 8, 2012
Summary
Liver dimensions correlate significantly with body parameters like BMI and body surface area. Surface fissures in 70% of livers may aid surgeons in safe liver segment resection.
Area of Science:
- Anatomy
- Surgical Anatomy
- Medical Imaging
Background:
- Liver size is known to correlate with body surface area.
- Understanding liver dimensions and morphology is crucial for surgical procedures.
- Surface features like fissures may indicate underlying vascular structures.
Purpose of the Study:
- To assess liver size and its relationship with various body parameters.
- To investigate the presence and significance of liver surface fissures for surgical planning.
- To establish correlations between liver dimensions and anthropometric measurements.
Main Methods:
- Acquisition of 50 normal liver specimens from cadavers (aged 19-65 years).
- Measurement of liver diameters using Vernier Calipers and liver volume via water displacement.
- Statistical analysis including calculation of means, standard deviations, and correlation coefficients with body parameters.
Main Results:
- Significant correlations found between liver dimensions (anteroposterior diameter, vertical diameter at falciform ligament) and body mass index and body weight.
- A highly significant correlation (P < 0.001) was observed between liver volume and body surface area.
- Surface fissures, demarcating vascular segments, were present in 70% of specimens, with underlying veins noted in 40%.
Conclusions:
- Liver dimensions increase proportionally with body parameters.
- Morphological study of the liver, including surface fissures, can enhance surgical safety by guiding dissection planes.
- Identified fissures can assist surgeons in precise liver segment resection.
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