Use of collagen in extraoral wounds

The basic fundamental elements that collagen bring into the wound activity are its hemostatic effect, its interaction with platelets and interaction with fibronection, increase in fluid exudates, increase in cellular components (macrophages) and support for fibroblastic proliferation into wound activity. In this way collagen plays a significant parts in almost every function of the body. Previously broad use of collagen was stifled because of cost, recent advances made it possible to develop cost effective collagen. In this study twenty patients of maxillofacial wounds were treated with the use of collagen. The results were satisfactory without any significant complication.