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Updated: May 17, 2026
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Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
Published on: April 13, 2022
Developments in autotransplantation of teeth
David Cross1, Ahmed El-Angbawi, Paul McLaughlin
1The Dental School, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK. David.Cross@glasgow.ac.uk
Summary
Tooth transplantation, including allotransplants and autotransplants, has a long history with modern techniques improving success rates. Autotransplants offer advantages over implants, especially for children.
Area of Science:
- Dentistry
- Oral Surgery
- Regenerative Medicine
Background:
- Tooth transplantation has been practiced for centuries, with early 18th-19th century allotransplants lasting an average of 6 years.
- Autotransplantation gained traction in Scandinavia during the mid-20th century under controlled conditions, showing long-term success up to 45 years.
Observation:
- Modern advancements include cone beam CT and 3D prototyping for precise surgical templates.
- These technologies minimize the extra-oral time for transplanted teeth, enhancing survival rates.
Findings:
- Autotransplantation demonstrates significant long-term viability, with survival rates up to 45 years.
- Recent technological improvements are expected to further increase the success of tooth transplantation.
Implications:
- Autotransplanted teeth present considerable advantages over single-tooth implants.
- Tooth autotransplantation should be considered the primary treatment option for tooth replacement in growing children.
