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Updated: May 16, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Penumbral imaging by using perfusion computed tomography and perfusion-weighted magnetic resonance imaging: current
Makoto Sasaki1, Kohsuke Kudo, Soren Christensen
1Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Nishitokuta, Yahaba, Japan.
Abstract:
Perfusion computed tomography and perfusion-weighted magnetic resonance imaging are used to evaluate the extent of the area with ischemic penumbra; however, different parameters, algorithms, and software packages show significant discrepancies in the size of perfusion abnormalities, which should be minimized. Recently, cross-validation studies were performed using digital phantoms and have elucidated the precision and reliability of various penumbral imaging techniques. These research initiatives can promote further multicenter trials on recanalization therapies by providing accurate inclusion/exclusion criteria for appropriate patient selection.
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